Ammonia measurement in cirrhosis: International Delphi consensus recommendations from ISHEN

Maria Pilar Ballester, Rocío Gallego-Durán, Shalimar, Karen Louise Thomsen, Constantine J Karvellas, Srinivasan Dasarathy, Debbie L Shawcross, Dominique Thabut, Jinjun Chen, Christopher F Rose, Rajiv Jalan

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The dual roles of natural killer cells in liver immunity and tolerance: Implications for health and disease

Zhongheng Li, Yihang Gong, Linsen Ye, Wei Liu

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Acute-on-chronic liver failure and immune dysregulation: Systemic inflammation and immunoparesis paradox

Abigail A Drago, Sarah Yanofsky, Ramsey Rohner, Kamal Baral, Leah Spade, Peng-Sheng Ting, Bilon Khambu

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Ileal Bile Acid Transporter Inhibitors in Cholestasis: Potential for More Than Just Paediatrics?

Mahesh Krishna, James Lorenzen Boyer

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PIEZO1 channel mechanosensing in hepatobiliary physiology and disease

Charalampos Konstantinou, Shaili K Patel, Patricia Lalor, J Bernadette Moore, Lee D Roberts, Naima Endesh, Tze M Wah, Adel Samson, Abdul R Hakeem, Kondragunta R Prasad, David J Beech, Laeticia Lichtenstein

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Hepatocyte-hepatic stellate cell interactions in liver fibrosis: Mechanisms and therapeutic implications

Zihan Wang, Zixuan Cao, Yunsheng Dong, Yi Hong, Li Zuo, Hua Wang

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Massive hepatic necrosis-associated acute liver failure

Tao Lin, Chenhao Tong, Roman Liebe, Honglei Weng

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Medical Management of Polycystic Liver Disease: A Position Statement From the European Reference Network on Hepatological Diseases

Sophia Heinrich, Andreia Margarida Carvalho de Matos, Jordi Colmenero, Ahmed M Elsharkawy, Soňa Fraňková, Jan Halbritter, Anna Mrzljak, Roman-Ulrich Müller, Rafaela Pereira, Pavel Strnad, Carmen A J Teemer, Jef Verbeek, Karolina M Wronka, Frederik Nevens, Richard Taubert, Joost P H Drenth; European Reference Network on Hepatological Liver Diseases (ERN RARE‐LIVER)

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Liver as a key organ for systemic antimicrobial defense

Tiantian Yao, Luca Maccioni, Yukun Guan, Robim M Rodrigues, Bin Gao

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EASL Clinical Practice Guidelines on vascular diseases of the liver

European Association for the Study of the Liver

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The role of Liver Sinusoidal Endothelial Cells in liver diseases: key players in health and pathology

Eric Felli, Yeldos Nulan, Martí Ortega-Ribera, Anabel Fernández-Iglesias, Jordi Gracia-Sancho

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Haemostatic Balance and Transfusion Strategies in Acute Liver Failure and Acute-On-Chronic Liver Failure: A Systematic Review

Kymentie Ferdinande, Elena Campello, Paolo Simioni, Alberto Zanetto, Marco Senzolo

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Diagnosing Autoimmune Hepatitis: Histological Correlations and Emerging Technologies

Giorgio Cazzaniga, Francesca Bolis, Chiara Caime, Rocco Piazza, Laura Žigutytė, Jakob Nikolas Kather, Fabio Pagni, Pietro Invernizzi, Marco Carbone, Alessio Gerussi

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Cellular Senescence in Liver Diseases: From Molecular Drivers to Therapeutic Targeting

Kuo Du, David S Umbaugh, Niansheng Ren, Anna Mae Diehl

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Myeloid cells in chronic liver inflammation

Dimitrios Patseas, Ahmed El-Masry, Zuobin Liu, Prakash Ramachandran, Evangelos Triantafyllou

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Pathogenesis, Non-Invasive Assessments and Treatment of Hepatic Fibrosis in Autoimmune Liver Diseases

Ellina Lytvyak, Gideon Hirschfield, Devika Shreekumar, Yu Jun Wong, Aldo J Montano-Loza

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Communication initiated by hepatocytes: The driver of HSC activation and liver fibrosis

Ruichao Lan, Jun Lin, Shuai Chen, Zhi Lu, Yihang Gong, Siwei Tan, Xianzhi Liu, Weiling He

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Benefits and challenges to therapeutic targeting of bile acid circulation in cholestatic liver disease

Michael Trauner, Saul J Karpen, Paul A Dawson

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Inflammation and immunity in liver homeostasis and disease: a nexus of hepatocytes, nonparenchymal cells and immune cells

Enis Kostallari, Robert F Schwabe, Adrien Guillot

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Chimeric Antigen Receptor (CAR) T-cell Therapy: Engineering Immune Cells To Treat Liver Diseases

Elmar Jaeckel, Scott L Friedman, Michael Hudecek, Ulrike Protzer

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Enteronephrohepatic Circulation of Bile Acids and Therapeutic Potential of Systemic Bile Acid Transporter Inhibitors

Ahmed Ghallab, Mattias Mandorfer, Guido Stirnimann, Joachim Geyer, Erik Lindström, Tom Luedde, Schalk van der Merwe, Jassin Rashidi-Alavijeh, Hartmut Schmidt, Saul J Karpen, Peter Fickert, Michael Trauner, Jan G Hengstler, Paul A Dawson

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Hepatocyte Nuclear Factor 4 Alpha: A Key Regulator of Liver Disease Pathology and Haemostatic Disorders

Subhadip Choudhuri, Nisha Jain Garg

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Role of mitogens in normal and pathological liver regeneration

Massoud Vosough, Bahare Shokouhian, Mohammad Amin Sharbaf, Roya Solhi, Zahra Heidari, Homeyra Seydi, Moustapha Hassan, Ezhilarasan Devaraj, Mustapha Najimi

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Natural History of Idiosyncratic Drug-Induced Liver Injury and Prognostic Models

Harshad C Devarbhavi, Raúl J Andrade

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EASL Clinical Practice Guidelines on the management of autoimmune hepatitis

European Association for the Study of the Liver

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Portal sinusoidal vascular diseases: Assessment and therapy

Maria Mironova, Harish Gopalakrishna, Christopher Koh, David E Kleiner, Theo Heller

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Cell therapies and liver organogenesis technologies: Promising strategies for end-stage liver disease

Shaoyang Qin, Xiaochen Bo, Hongyuan Liu, Zhishuo Zhang, Zhicong Zhao, Qiang Xia

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Advances in imaging – Elastography

Elton Dajti, Adrian T Huber, Giovanna Ferraioli, Annalisa Berzigotti

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Unravelling the Role of PANoptosis in Liver Diseases: Mechanisms and Therapeutic Implications

Wanyuan Xiong, Junfeng Li, Aiping Tian, Xiaorong Mao

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Regulatory T cell therapy in autoimmune liver disease and transplantation

M Fleming, A Sanchez-Fueyo, N Safinia

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Hot and Cold Fibrosis: The Role of Serum Biomarkers to assess the Immune Mechanisms and ECM-Cell Interactions in Human Fibrosis

A Zawadzki, D J Leeming, A J Sanyal, Q M Anstee, J M Schattenberg, S L Friedman, S D Schuppan, M A Karsdal

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Peroxisome proliferator-activated receptor delta and liver diseases

Tomoo Yamazaki, Edward E Cable, Bernd Schnabl

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Neurogastroenterology and motility disorders in patients with cirrhosis

Francisco Idalsoaga, Gustavo Ayares, Hanna Blaney, Daniel Cabrera, Javier Chahuan, Hugo Monrroy, Ayah Matar, Houssam Halawi, Marco Arrese, Juan Pablo Arab, Luis Antonio Díaz

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The evolving role of liver biopsy: Current applications and future prospects

Purva Gopal, Xiaobang Hu, Marie E Robert, Xuchen Zhang

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The immunological landscape of primary biliary cholangitis: Mechanisms and therapeutic prospects

Vincenzo Ronca, Scott P Davies, Ye Htun Oo, Ana Lleo

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Thyroid hormone and the Liver

Lorraine Soares De Oliveira, Megan J Ritter

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PPAR agonists for the treatment of cholestatic liver diseases: Over a decade of clinical progress

Colleen M Hayes, Gina M Gallucci, James L Boyer, David N Assis, Nisanne S Ghonem

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Key role of macrophages in the progression of hepatic fibrosis

Jinqiu Ran, Shengxia Yin, Rahma Issa, Qianwen Zhao, Guangqi Zhu, Huan Zhang, Qun Zhang, Chao Wu, Jie Li

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